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  • About The File:
    File Format | PDF
    File Size | 14.3 MB
    Pages | 305
    Language | English
    Category | Pharmacology
    Description:  Great for course review and the USMLE Step 1, Pharmacology PreTest asks the right questions so you’ll know the right answers. You’ll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers.

    The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest!.
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  • About The File:
    File Format | PDF
    File Size | 12.4 MB
    Pages | 626
    Language | English
    Category | Clinical
    Description:  Modern medicine is highly complex and investigations are a key part of the diagnostic process. With major advances in technology there are thousands of clinical and laboratory tests available. This book provides a patient-oriented approach to investigation (first part of book) where key symptoms and signs are described along with tests that may be of value in reaching a diagnosis.

    The remainder of the book is specialty-centred and provides a comprehensive review of all available tests within a given subject. The book emphasises which tests are of value, when tests are not likely to be helpful, along with pitfalls in the interpretation of results.

    The aim is of the book is to provide a more rational method of investigation and prevent over-investigation which is expensive for the hospital and unpleasant for the patient. The contributors are all active clinicians who are engaged in medical practice, so appreciate the problems faced by junior doctors.
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  • About The File:
    File Format | PDF
    File Size | 2.78 MB
    Pages | 730
    Language | English
    Category | Emergency
    Description:  This is an excellent resource for poison control centers, toxicologists, and healthcare practitioners for the diagnosis, treatment, and management of poisonings as a result of exposure to a wide variety of industrial, therapeutic, illicit, and environmental chemicals. Doody's Review Service

    With each bestselling edition, Poisoning & Drug Overdose has helped poison control staff, medical toxicologists, and emergency physicians respond to drug-related emergencies and chemical exposures. The new edition of this exceptional, at-a-glance guide offers the latest advice needed for the effective diagnosis and treatment of poisoning and drug overdose.

    The Fifth Edition features:
    Critical insights into timely topics such as biological warfare agents and the newest antidotes
    Updated information on industrial chemicals, including the most recent regulatory exposure limits
    Expanded information, including special pregnancy considerations
    Easy-to-read text and tables containing specific drug dosage information
    Detailed table summarizing current toxicity and workplace exposure guidelines for more than 500 industrial chemicals
    Extensive cross-referencing
    Comprehensive index featuring generic, chemical, and brand names for many drugs and commercial products
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  • About The File:
    File Format | PDF
    File Size | 16.8 MB
    Pages | 366
    Language | English
    Category | Pharmacology
    Description:  Advances in molecular biology and recombinant DNA technology have accelerated progress in many fields of life science research, including gene therapy. A large number of genetic engineering approaches and methods are readily available for gene cloning and therapeutic vector construction. Significant progress is being made in genomic, DNA sequencing, gene expression, gene delivery and cloning. Thus gene therapy has already shown that it holds great promise for the treatment of many diseases and disorders. In general it involves the delivery of recombinant genes or transgenes into somatic cells to replace proteins with a genetic defect or to transfer with the pathological process of an illness. The viral and non-viral delivery systems may hold the potential for future non-invasive, cost-effective oral therapy of genetically-based disorders.

    Recent years have seen considerable progress in the discovery and early clinical development of a variety of gene therapeutic products. The availability, validation, and implementation of gene therapeutic products has also enabled success in testing and evaluation. New challenges will need to be overcome to ensure that products will also be successful in later clinical development and ultimately for marketing authorisation. These new challenges will include improvements in delivery systems, better control of in-vivo targeting, increased level transduction and duration of expression of the gene, and manufacturing process efficiencies that enable reduction in production costs. Perhaps profound understanding of regulated gene design may result in innovative bioproducts exhibiting safety and efficacy profiles that are significantly superior to those achieved by the use of naturally occurring genes. This procedure may contribute considerably to fulfilling standards set by regulatory authorities.
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  • About The File:
    File Format | PDF
    File Size | 9.22 MB
    Pages | 201
    Language | English
    Category | Chemistry
    Description:  The purpose of this book is to provide the user with a concise summary of the physical properties, detection methods, handling precautions and of the biochemical and physiological effects of gases and fumes found in the working environment so that they may be handled safely.

    The substances dealt with in this book vary considerably in their properties, whether it be chemical, physical or physiological, and as a consequence in the risks they pose to health and safety and the conditions demanded of staff and workplaces which handle them. It is therefore important not only to be able to identify both the gases and fumes themselves, but the dangers which they pose and the consequent measures necessary to deal with those dangers, whether it be as a precautionary measure or in response to an incident. For these reasons the availability of the data contained in this extremely useful book will be of vital importance to all staff on sites where such substances are used as well as too those who may need to react to an accident involving their use such as fire-fighters, doctors, nurses, paramedics and other emergency response staff.
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  • About The File:
    File Format | PDF
    File Size | 4.21 MB
    Pages | 1163
    Language | English
    Category | Pharmacology
    Description:  This handbook, which in its early lustrous years served physicians, pharmacists, and pharmacy students, is unlike any other drug reference book in that it allows readers to compare and contrast various drugs within drug categories, thereby enabling them to make decisions on which drug to administer. All other drug reference books merely repeat the drug manufacturers' literature, with no analysis of that information. Nor are there any reports from the published literature concerning use and efficacy of the drugs listed. The clinical drug information with part II contains chapters on drug-induced diseases, drug interactions and interferences, drug use in special populations, immunization, medical emergencies, and nutrition support. There are also appendices that contain useful conversion factors, anthropometrics, and laboratory indices.

    Unique Features:
    Comprehensive comparison charts of drugs by class for easy clinical decision making
    Tables that help rapidly identify the cause of adverse drug effects in your patients
    Guides to the optimal choice of drugs in special populations, such as pregnant and breastfeeding women, renal disease, and dialysis
    The only referenced drug handbook--includes over 3,600 literature citations
    Tabbing guide for easy location of drug categories
    Extensive cross-referenced index that includes Canadian and British drug names
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  • About The File:
    File Format | PDF
    File Size | 18.8 MB
    Pages | 401
    Language | English
    Category | Chemistry
    Description:  Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates.
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  • About The File:
    File Format | PDF
    File Size | 13.1 MB
    Pages | 362
    Language | English
    Category | Biochemical
    Description:  This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. 

    This book uses the tools of statistical mechanics to present the molecular theory of cooperativity. Cooperativity is used in a variety of processes-such as loading and unloading of oxygen at relatively small pressure differences; maintaining an almost constant concentration of various compounds in living cells; and switching on and off the reading of genetic information.

    This book may be used as a textbook by graduate students in Chemistry, Biochemistry and Biophysics, and will also be of interest to researchers in theoretical biochemistry.
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  • About The File:
    File Format | PDF
    File Size | 3.08 MB
    Pages | 1006
    Language | English
    Category | Pharmacology
    Description:  The busy healthcare practitioner's first reference for timely, accurate, and relevant drug information. Alphabetically organized by generic name (with trade names cross-referenced) and presented in an at-a-glance drug chart format. All entries are reviewed by an editorial advisory board of academic an clinical authorities.
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  • About The File:
    File Format | PDF
    File Size | 26.3 MB
    Pages | 513
    Language | English
    Category | Pharmacology
    Description:  This book provides a unique and up-to-date insight into the biopharmaceutical industry. Largely written by industrial authors, its scope is multidisciplinary, rendering it an ideal reference source for students undertaking advanced undergraduate or postgraduate courses in biotechnology, pharmaceutical science, biochemistry, or medicine.
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  • About The File:
    File Format | PDF
    File Size | 6.03 MB
    Pages | 481
    Language | English
    Category | Chemistry
    Description:  Quality measurement, control, and improvement in combinatorial chemistry
    Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable."
    To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries.

    A new volume in Chemical Analysis series, this text has four parts covering:
    * Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis
    * High-throughput analytical methods used to analyze the quality of libraries
    * High-throughput purification techniques
    * Analytical methods applied in post-synthesis and post-purification stages

    Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques.
    This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.
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  • About The File:
    File Format | PDF
    File Size | 9.86 MB
    Pages | 958
    Language | English
    Category | Pharmacology
    Description:  This popular core nursing pharmacology textbook provides unique coverage of nursing interventions for drug therapy with related rationales. Highly praised for its organized and readable presentation, the text explains the "why" behind each nursing action, and emphasizes how drugs work differently in different patients.  The 10th edition has a new fresh design and approach with an added focus on patient safety integrated into the text.
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  • About The File:
    File Format | PDF
    File Size | 6.92 MB
    Pages | 402
    Language | English
    Category | Pain Medicine
    Description:  A quick reference to the management of pain for specialists as well as general medical practitioners and residents. Written in a concise bulleted format, the content is limited to only the essential facts necessary for assessment and treatment of common pain conditions and presentations. A perfect review tool for both the anesthesia and pain medicine board exams.
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  • About The File:
    File Format | PDF
    File Size | 6.73 MB
    Pages | 531
    Language | English
    Category | Neurology
    Description:  Neurotransmitters, Drugs and Brain Function aims to link basic aspects of the activity of neurotransmitters at the receptor and synaptic level with their role in normal brain function, disease states, and drug action. Thus, the material considers to what extent our knowledge of the central synaptic action of certain drugs can explain their possible roles in the cause of diseases and in the modes of action of drugs effective in those conditions.

    It offers a working explanation of drug and neurotransmitter action in CNS function, with a clear, comprehensive, and challenging style of writing. The authors review the chemical basis for drugs and the conditions they treat. It also, includes numerous illustrations and schematic diagrams.
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  • About The File:
    File Format | PDF
    File Size | 22.0 MB
    Pages | 582
    Language | English
    Category | Neurology
    Description:  Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters.

    Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike.

    . Comprehensive review of OXT and AVP physiology and behaviour
    . Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert
    . Review articles are ideal for experts and newcomers to the field alike
    . Discusses fascinating behavioural effects of oxytocin and vasopressin
    . Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location
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